Genes are partially to blame for which coronavirus symptoms people experience, according to a new study that used twins to explore how genetics impact the virus’ response in patients.
The study, which was not peer-reviewed, looked at 2,633 identical and fraternal twins who were diagnosed with COVID-19, according to a report in the pre-publication server MedRix.
“The idea was to basically look at the similarities in symptoms or non-symptoms between the identical twins, who share 100 percent of their genes, and the non-identical twins, who only share half of their genes,” King’s College London Professor Tim Spector, one of the researchers, told the Guardian.
The research group asked twins participating in another study to upload their symptoms to an app that tracks the illness.
The team took into account whether the twins lived in the same household as well as whether they had contact with one other, the report said.
Researchers determined genes were 50-percent responsible for whether participants suffered symptoms such as fever, diarrhea and delirium — as well as the loss of taste and smell.
“This disease is very weird, the way it has a very different presentation in the population in different people – what we are showing is that isn’t random,” Spector told the Guardian. “It is not mainly due to where you live or who you have seen; a lot of it is something innate about you.
However, other symptoms, such as cough, lack of appetite, chest pain, and abdominal pain, didn’t prove to be related to genetics, according to the researchers, who attributed them to other factors, such as the surrounding environment.
Researchers said the findings could help others work to find out why the virus impacts some people severely while others show no symptoms.
“It reassures everyone that it is worth exploring this whole triangle of genes, immune system and gut microbes,” Spector told the outlet.
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April 27, 2020 at 11:30PM
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Study of twins reveals genetic impact on coronavirus symptoms - New York Post
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